STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Celf_1588PFAM: Peptidoglycan-binding lysin domain; KEGG: peptidoglycan-binding lysin domain protein. (152 aa)    
Predicted Functional Partners:
lexA
Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.693
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.558
Celf_1637
KEGG: hypothetical protein.
 
   
 0.510
Celf_0719
KEGG: hypothetical protein.
  
     0.478
Celf_0734
KEGG: hypothetical protein.
  
     0.462
Celf_2207
KEGG: hypothetical protein.
  
     0.459
Celf_2775
KEGG: hypothetical protein.
  
     0.459
Celf_0026
KEGG: sortase family protein; TIGRFAM: sortase family protein; PFAM: peptidase C60 sortase A and B.
  
   
 0.440
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
   
   0.431
Celf_0633
KEGG: hypothetical protein.
  
     0.421
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.