STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Celf_2139KEGG: aconitate hydratase 1; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain-containing protein. (936 aa)    
Predicted Functional Partners:
Celf_2552
KEGG: bcv:Bcav_0574 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.998
Celf_2892
TIGRFAM: citrate synthase I; KEGG: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.997
Celf_1122
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.993
Celf_2655
KEGG: 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain-containing protein of components of various dehydrogenase complexes.
 
 0.975
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.965
Celf_2127
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; KEGG: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.
   
 0.963
Celf_2551
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
  
 0.938
Celf_2550
KEGG: bcv:Bcav_0567 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein.
  
 
 0.934
Celf_2830
KEGG: isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.
   
 
 0.934
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.874
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
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