node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Celf_0460 | Celf_2349 | Celf_0460 | Celf_2349 | KEGG: chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.457 |
Celf_0460 | hrcA | Celf_0460 | Celf_2351 | KEGG: chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.814 |
Celf_1967 | Celf_2349 | Celf_1967 | Celf_2349 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.673 |
Celf_1967 | miaB | Celf_1967 | Celf_1575 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.782 |
Celf_1967 | rsmH | Celf_1967 | Celf_1608 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.534 |
Celf_1967 | rsmI | Celf_1967 | Celf_3079 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.510 |
Celf_1967 | trmB | Celf_1967 | Celf_3541 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.662 |
Celf_1967 | trmD | Celf_1967 | Celf_1504 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.605 |
Celf_2349 | Celf_0460 | Celf_2349 | Celf_0460 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | KEGG: chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | 0.457 |
Celf_2349 | Celf_1967 | Celf_2349 | Celf_1967 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.673 |
Celf_2349 | Celf_2352 | Celf_2349 | Celf_2352 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | KEGG: hypothetical protein. | 0.611 |
Celf_2349 | dnaJ | Celf_2349 | Celf_2350 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.899 |
Celf_2349 | hrcA | Celf_2349 | Celf_2351 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.908 |
Celf_2349 | miaB | Celf_2349 | Celf_1575 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.522 |
Celf_2349 | rsmH | Celf_2349 | Celf_1608 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.577 |
Celf_2349 | rsmI | Celf_2349 | Celf_3079 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.574 |
Celf_2349 | trmB | Celf_2349 | Celf_3541 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.472 |
Celf_2349 | trmD | Celf_2349 | Celf_1504 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.469 |
Celf_2352 | Celf_2349 | Celf_2352 | Celf_2349 | KEGG: hypothetical protein. | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.611 |
Celf_2352 | dnaJ | Celf_2352 | Celf_2350 | KEGG: hypothetical protein. | Chaperone DnaJ domain protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between [...] | 0.614 |