STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbhBGlycoside hydrolase family 48; Hydrolyzes cellohexaose to a mixture of cellotetraose, cellotriose and cellobiose, with only a trace of glucose. It hydrolyzed cellopentaose to cellotriose and cellobiose, and cellotetraose to cellobiose, but it did not hydrolyze cellotriose. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion of anomeric configuration; Belongs to the glycosyl hydrolase 48 (cellulase L) family. (1090 aa)    
Predicted Functional Partners:
Celf_0088
Endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; cellulose-binding family II; KEGG: endo-1,4-beta-xylanase; SMART: glycoside hydrolase family 10; cellulose-binding family II.
     0.752
cenC
Glycoside hydrolase family 9; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
  
   
 0.688
Celf_3156
Endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; Ricin B lectin; KEGG: endo-1,4-beta-xylanase; SMART: glycoside hydrolase family 10; Ricin B lectin.
     0.681
Celf_0404
KEGG: cellulose-binding family II; PFAM: cellulose-binding family II; SMART: cellulose-binding family II.
  
     0.661
Celf_0398
KEGG: pectate lyase; PFAM: Pectate lyase; Ricin B lectin; SMART: Ricin B lectin.
 
   0.642
Celf_1340
KEGG: pectate lyase; PFAM: Pectate lyase; Ricin B lectin; SMART: Ricin B lectin.
 
   0.575
Celf_2974
KEGG: xce:Xcel_2668 adenylyl cyclase class-3/4/guanylyl cyclase.
  
     0.528
Celf_0376
Cellulase; KEGG: xce:Xcel_0182 cellulase; PFAM: glycoside hydrolase family 5; protein of unknown function DUF291; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
  
 0.522
Celf_3155
Alpha-N-arabinofuranosidase; PFAM: Ricin B lectin; KEGG: scb:SCAB_79241 putative arabinofuranosidase; SMART: Ricin B lectin.
  
     0.505
cbhA
1, 4-beta cellobiohydrolase; This enzyme hydrolyzes 1,4-beta-D-glucosidic linkages of cellulose. Weak activity against carboxymethylcellulose, bacterial microcrystalline cellulose and barley beta-glucan. Has also weak endoglucanase activity. Hydrolyzes glucosidic bonds with inversion of anomeric configuration; Belongs to the glycosyl hydrolase 6 (cellulase B) family.
 
   
0.498
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
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