Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB46525.1Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: cba:CLB_1645 aco operon transcriptional regulator. (639 aa)    
Predicted Functional Partners:
ADB46524.1
PFAM: NLP/P60 protein; Peptidoglycan-binding domain 1 protein; KEGG: cce:Ccel_2940 NLP/P60 protein.
       0.707
ADB48406.1
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; KEGG: hmo:HM1_1310 RNA polymerase sigma-54 factor.
 
  
 0.703
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
     
 0.640
ADB48078.1
PFAM: sulfatase; KEGG: emi:Emin_0565 sulfatase.
  
     0.630
ADB48013.1
Hypothetical protein.
  
     0.613
ADB48033.1
PFAM: OstA family protein; KEGG: lba:Lebu_2045 OstA family protein.
  
     0.589
ADB47232.1
KEGG: sth:STH1851 hypothetical protein.
  
     0.586
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
   
 0.583
ADB47877.1
KEGG: tpd:Teth39_1436 hypothetical protein.
  
  
 0.577
ADB47055.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0565 multi-sensor hybrid histidine kinase.
  
 
 0.571
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.