Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB46532.1PFAM: protein of unknown function DUF190; KEGG: dsa:Desal_1826 protein of unknown function DUF190. (131 aa)    
Predicted Functional Partners:
crcB-2
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
     0.543
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.526
ADB48078.1
PFAM: sulfatase; KEGG: emi:Emin_0565 sulfatase.
  
     0.472
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
     0.456
ADB46531.1
KEGG: gwc:GWCH70_1791 hypothetical protein.
       0.423
ADB48215.1
KEGG: cpi:Cpin_2966 hypothetical protein.
  
     0.421
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (12%) [HD]