Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB46605.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: tna:CTN_0365 oxidoreductase, short chain dehydrogenase/reductase family. (251 aa)    
Predicted Functional Partners:
ADB46606.1
Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.
     
 0.767
ADB46602.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 
 0.685
ADB47932.1
PFAM: acyl-CoA dehydrogenase domain protein; Electron transfer flavoprotein alpha subunit; Rubredoxin- type Fe(Cys)4 protein; KEGG: cbi:CLJ_B3073 acyl-CoA dehydrogenase family protein/electron transfer protein.
  
 0.675
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.614
ADB46604.1
PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: pjd:Pjdr2_5748 cold-shock DNA-binding domain protein.
  
 
 0.592
ADB47749.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.581
ADB47055.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0565 multi-sensor hybrid histidine kinase.
   
 
 0.571
ADB47753.1
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: drm:Dred_2073 malonyl CoA-acyl carrier protein transacylase.
 
 0.569
ADB46607.1
Hypothetical protein; KEGG: azc:AZC_3961 outer membrane protein Omp31 precursor.
  
  
 0.563
ADB47636.1
PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; KEGG: cdf:CD2335 inosine 5-monophosphate dehydrogenase.
   
 
 0.546
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (12%) [HD]