Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB46633.1PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: bvu:BVU_0349 thiamine biosynthesis protein ThiH. (473 aa)    
Predicted Functional Partners:
ADB47613.1
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: cth:Cthe_0042 small GTP-binding protein.
  
 0.955
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.847
ADB47249.1
KEGG: ere:EUBREC_0233 hypothetical protein.
 
     0.767
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.752
ADB48194.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: dth:DICTH_0761 anti-sigma regulatory factor.
   
    0.742
ADB47561.1
PFAM: thiamine monophosphate synthase; KEGG: ere:EUBREC_0222 thiamine-phosphate pyrophosphorylase, putative.
  
  
 0.700
ADB48307.1
TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; KEGG: cbt:CLH_1644 iron hydrogenase 1.
 
   
 0.635
ADB47890.1
PFAM: hydrogenase large subunit domain protein; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: nth:Nther_0884 hydrogenase large subunit domain protein.
 
   
 0.540
ADB48245.1
PFAM: hydrogenase large subunit domain protein; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: dhd:Dhaf_0813 hydrogenase large subunit domain protein.
 
   
 0.511
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.486
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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