Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB46645.1PFAM: Formiminotransferase-cyclodeaminase; KEGG: ctc:CTC02303 formiminotetrahydrofolate cyclodeaminase. (206 aa)    
Predicted Functional Partners:
ADB46643.1
KEGG: ctc:CTC02305 glutamate formiminotransferase; TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein.
 
  0.999
fhs
PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: ctc:CTC02304 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
 
  
 0.984
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.942
ADB47702.1
IMP cyclohydrolase; KEGG: bfr:BF2666 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme formylation region; SMART: AICARFT/IMPCHase bienzyme formylation region.
 
  
  0.912
ADB47881.1
TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: cno:NT01CX_1657 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
    
  0.911
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
  0.900
ADB46724.1
KEGG: sat:SYN_01763 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
      0.670
ADB46642.1
PFAM: protein of unknown function DUF886; KEGG: tde:TDE2575 hypothetical protein.
 
     0.557
ADB46646.1
PFAM: transposase IS4 family protein; KEGG: dsy:DSY1297 hypothetical protein.
       0.531
ADB48204.1
PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12- binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: aoe:Clos_0080 homocysteine S- methyltransferase.
  
  
 0.433
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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