Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB46710.1TIGRFAM: siroheme synthase; KEGG: ttu:TERTU_1974 siroheme synthase. (192 aa)    
Predicted Functional Partners:
ADB46709.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: mta:Moth_1248 uroporphyrinogen-III C- methyltransferase / uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
 
 0.999
ADB46708.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.947
ADB46707.1
PFAM: BioY protein; KEGG: dae:Dtox_4332 BioY protein.
       0.777
ADB48093.1
PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: cpr:CPR_0512 nitrite/sulfite reductase-like protein.
 
  
 0.678
ADB48204.1
PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12- binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: aoe:Clos_0080 homocysteine S- methyltransferase.
  
  
 0.509
ADB46711.1
PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; KEGG: ctc:CTC00826 rubredoxin/rubrerythrin domain- containing protein.
       0.477
ADB47446.1
KEGG: ckr:CKR_3419 hypothetical protein.
  
  
 0.447
ADB46706.1
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: gme:Gmet_1684 LysR family transcriptional regulator.
       0.432
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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