Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB46951.1TIGRFAM: GTP-binding protein TypA; small GTP- binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; KEGG: cac:CAC1684 TypA/BipA type GTPase. (606 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.676
ADB46950.1
PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: cce:Ccel_1759 RNA-metabolising metallo-beta- lactamase.
       0.514
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
  
 0.496
ADB47697.1
PFAM: PP-loop domain protein; SMART: Rhodanese domain protein; KEGG: ere:EUBREC_1362 putative ATPase of the PP- loop superfamily implicated in cell cycle control; Belongs to the TtcA family.
  
    0.490
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
   
  
 0.481
infC
Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
 
 0.480
rpsI
PFAM: ribosomal protein S9; KEGG: cth:Cthe_1782 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
    0.475
rpmI
TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: ter:Tery_1881 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
  
    0.470
ADB46952.1
PFAM: protein of unknown function DUF552.
       0.468
rplA
Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
  
 0.460
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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