Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily. (289 aa)    
Predicted Functional Partners:
ADB46997.1
PFAM: YbbR family protein; KEGG: mta:Moth_2247 YbbR-like.
 
  
 0.935
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.882
ADB48294.1
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: drm:Dred_3126 phosphomannomutase.
   
 
 0.858
ADB46998.1
PFAM: FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: gme:Gmet_2676 FAD dependent oxidoreductase.
       0.784
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.553
ADB46451.1
Diguanylate cyclase and phosphoesterase; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
   
 0.537
ADB46995.1
TIGRFAM: amidohydrolase; PFAM: peptidase M20; KEGG: apr:Apre_0497 amidohydrolase.
       0.522
ADB46999.1
Inorganic diphosphatase; PFAM: DHHA2 domain protein; phosphoesterase RecJ domain protein; KEGG: cac:CAC2138 putative manganese-dependent inorganic pyrophosphatase.
       0.492
ADB47000.1
Hypothetical protein.
       0.463
ADB47714.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: sth:STH1524 exopolyphosphatase-related protein.
 
   
 0.430
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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