| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADB46759.1 | ADB47585.1 | Acfer_0353 | Acfer_1224 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: trq:TRQ2_0904 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | 0.473 |
| ADB46759.1 | ADB47777.1 | Acfer_0353 | Acfer_1418 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.537 |
| ADB46759.1 | guaA | Acfer_0353 | Acfer_0670 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.738 |
| ADB46759.1 | panC | Acfer_0353 | Acfer_0776 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.506 |
| ADB46759.1 | scpA | Acfer_0353 | Acfer_1245 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.444 |
| ADB47163.1 | panC | Acfer_0775 | Acfer_0776 | PFAM: Bile acid:sodium symporter; KEGG: oih:OB0994 sodium-dependent transporter. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.782 |
| ADB47585.1 | ADB46759.1 | Acfer_1224 | Acfer_0353 | KEGG: trq:TRQ2_0904 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.473 |
| ADB47585.1 | panC | Acfer_1224 | Acfer_0776 | KEGG: trq:TRQ2_0904 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.452 |
| ADB47729.1 | panC | Acfer_1369 | Acfer_0776 | Amidase, hydantoinase/carbamoylase family; KEGG: gau:GAU_3178 putative N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.900 |
| ADB47777.1 | ADB46759.1 | Acfer_1418 | Acfer_0353 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.537 |
| ADB47777.1 | coaX | Acfer_1418 | Acfer_1593 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.922 |
| ADB47777.1 | panC | Acfer_1418 | Acfer_0776 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.905 |
| cinA | panC | Acfer_1016 | Acfer_0776 | TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: dth:DICTH_1766 competence-damage inducible protein; Belongs to the CinA family. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.476 |
| cmk | guaA | Acfer_1241 | Acfer_0670 | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; KEGG: esi:Exig_1808 cytidylate kinase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.509 |
| cmk | panC | Acfer_1241 | Acfer_0776 | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; KEGG: esi:Exig_1808 cytidylate kinase. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.904 |
| cmk | scpA | Acfer_1241 | Acfer_1245 | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; KEGG: esi:Exig_1808 cytidylate kinase. | Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.892 |
| coaX | ADB47777.1 | Acfer_1593 | Acfer_1418 | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.922 |
| coaX | panC | Acfer_1593 | Acfer_0776 | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.953 |
| guaA | ADB46759.1 | Acfer_0670 | Acfer_0353 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.738 |
| guaA | cmk | Acfer_0670 | Acfer_1241 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; KEGG: esi:Exig_1808 cytidylate kinase. | 0.509 |