Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)    
Predicted Functional Partners:
coaX
Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.953
ADB47777.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.905
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; KEGG: esi:Exig_1808 cytidylate kinase.
      0.904
ADB47729.1
Amidase, hydantoinase/carbamoylase family; KEGG: gau:GAU_3178 putative N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein.
     
  0.900
ADB47163.1
PFAM: Bile acid:sodium symporter; KEGG: oih:OB0994 sodium-dependent transporter.
     
 0.782
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.561
ADB46759.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.506
cinA
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: dth:DICTH_1766 competence-damage inducible protein; Belongs to the CinA family.
     
 0.476
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
    0.456
ADB47585.1
KEGG: trq:TRQ2_0904 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropter idinepyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK.
 
   
 0.452
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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