Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB47183.1KEGG: lga:LGAS_1558 hypothetical protein. (523 aa)    
Predicted Functional Partners:
ADB47184.1
KEGG: lac:LBA0469 hypothetical protein.
 
     0.953
ADB47185.1
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: lga:LGAS_1556 Lhr-like helicase.
 
     0.947
ADB47186.1
TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: bad:BAD_0632 MATE efflux family protein.
       0.677
ADB47182.1
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: dvl:Dvul_2201 pyridoxamine kinase; Belongs to the pyridoxine kinase family.
 
     0.568
ADB46836.1
KEGG: sca:Sca_2326 hypothetical protein.
  
     0.502
ADB47620.1
PFAM: tetracycline resistance leader peptide; KEGG: cbt:CLH_2455 hypothetical protein.
  
     0.490
ADB47861.1
PFAM: tetracycline resistance leader peptide; KEGG: cbt:CLH_2455 hypothetical protein.
  
     0.473
ADB47799.1
KEGG: fps:FP0848 hypothetical protein.
  
     0.448
ADB46786.1
PFAM: Haemagluttinin domain protein; Hep_Hag repeat- containing protein; YadA domain protein; S-layer domain protein; KEGG: pmu:PM0714 Hsf.
  
     0.440
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
   
    0.433
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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