Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB47187.1Diguanylate cyclase with PAS/PAC sensor; KEGG: pca:Pcar_0936 GGDEF domain-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein. (302 aa)    
Predicted Functional Partners:
ADB47646.1
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: lbu:LBUL_0889 C-di-GMP-specific phosphodiesterase.
 
 0.990
ADB47055.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0565 multi-sensor hybrid histidine kinase.
 
 
 0.976
ADB47800.1
Diguanylate cyclase; KEGG: cdf:CD0522 putative signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
0.918
ADB47256.1
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eel:EUBELI_20133 phosphoglucosamine mutase.
 
 0.900
ADB47746.1
Diguanylate cyclase; KEGG: gtn:GTNG_0884 methyl-accepting chemotaxis protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.894
ADB47747.1
KEGG: mpt:Mpe_A0214 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.894
ADB47078.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; KEGG: ele:Elen_1086 diguanylate cyclase/phosphodiesterase.
 
 0.887
ADB47817.1
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eat:EAT1b_1042 diguanylate cyclase and metal dependent phosphohydrolase.
 
 0.809
ADB47550.1
PFAM: type II and III secretion system protein; transport-associated; KEGG: bte:BTH_I2542 type II/III secretion system protein; Belongs to the bacterial secretin family.
  
    0.578
ADB46914.1
PFAM: type II secretion system protein E; KEGG: dac:Daci_1299 general secretory pathway protein E.
 
 
 0.545
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (16%) [HD]