Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB47256.1Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eel:EUBELI_20133 phosphoglucosamine mutase. (953 aa)    
Predicted Functional Partners:
ADB47187.1
Diguanylate cyclase with PAS/PAC sensor; KEGG: pca:Pcar_0936 GGDEF domain-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein.
 
 0.900
ADB47800.1
Diguanylate cyclase; KEGG: cdf:CD0522 putative signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
  
 0.888
ADB47746.1
Diguanylate cyclase; KEGG: gtn:GTNG_0884 methyl-accepting chemotaxis protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.813
ADB47747.1
KEGG: mpt:Mpe_A0214 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.812
ADB47055.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0565 multi-sensor hybrid histidine kinase.
 
 
 0.657
ADB46892.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cby:CLM_3126 pyruvate ferredoxin oxidoreductase.
     
 0.519
ADB47549.1
KEGG: nth:Nther_2317 response regulator receiver protein.
  
 
 0.492
ADB47817.1
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eat:EAT1b_1042 diguanylate cyclase and metal dependent phosphohydrolase.
 
    0.489
ADB47257.1
PFAM: flavodoxin/nitric oxide synthase; KEGG: cbl:CLK_0569 metallo-beta- lactamase/flavodoxin domain-containing protein.
  
    0.479
ADB47550.1
PFAM: type II and III secretion system protein; transport-associated; KEGG: bte:BTH_I2542 type II/III secretion system protein; Belongs to the bacterial secretin family.
  
    0.426
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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