Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB47323.1PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: dze:Dd1591_2702 oxidoreductase domain protein. (345 aa)    
Predicted Functional Partners:
ADB47322.1
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: histidine kinase A domain protein; ATP- binding region ATPase domain protein; KEGG: spk:MGAS9429_Spy0736 two-component system histidine kinase.
  
 
 0.727
lysS
TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; t-RNA-binding domain protein; KEGG: fma:FMG_0987 lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.715
ADB47321.1
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: lac:LBA1431 two-component response regulator.
     
 0.691
ADB47320.1
PFAM: RelA/SpoT domain protein; KEGG: lga:LGAS_0709 ppGpp synthetase/hydrolase catalytic subunit.
       0.588
ADB47319.1
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eel:EUBELI_01807 beta-phosphoglucomutase.
 
    0.544
ADB46892.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cby:CLM_3126 pyruvate ferredoxin oxidoreductase.
     
 0.516
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.506
ADB46544.1
KEGG: cbl:CLK_2222 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase.
 
     0.427
ADB46858.1
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bbe:BBR47_00410 PTS system IIA component.
 
  
 0.426
ADB46546.1
PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: cbb:CLD_3191 PTS system, IIBC components.
  
    0.419
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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