STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hgdHD-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the reduction of 2-oxoglutarate to 2- hydroxyglutarate. (331 aa)    
Predicted Functional Partners:
ADB46956.1
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; KEGG: bbe:BBR47_13840 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.970
ADB47407.1
PFAM: Lactate/malate dehydrogenase; KEGG: blt:Balat_0321 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.931
ADB47873.1
KEGG: drm:Dred_0735 beta-lactamase domain- containing protein.
 
 0.926
ADB46892.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cby:CLM_3126 pyruvate ferredoxin oxidoreductase.
    
 0.919
ADB48139.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.918
ADB47340.1
KEGG: shi:Shel_22660 Zn-dependent hydrolase, glyoxylase.
  
 0.915
ADB47177.1
KEGG: eel:EUBELI_20055 formate C-acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C- acetyltransferase glycine radical.
     
 0.913
ADB47085.1
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: chy:CHY_1369 NAD-dependent malic enzyme.
  
 
 0.908
ADB46484.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: nth:Nther_1482 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
    
  0.902
ADB46485.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tte:TTE1341 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
    
  0.902
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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