Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB47372.1Hypothetical protein. (30 aa)    
Predicted Functional Partners:
ADB47370.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.521
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.521
ADB47369.1
KEGG: csc:Csac_1189 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
       0.479
ADB47373.1
PFAM: PP-loop domain protein; KEGG: ckr:CKR_2212 hypothetical protein.
       0.470
ADB47374.1
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; KEGG: amt:Amet_0480 1-(5-phosphoribosyl)-5-amino-4- imidazole-carboxylate (AIR) carboxylase.
       0.470
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.470
ADB47376.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: cpy:Cphy_0681 cobalamin (vitamin B12) biosynthesis CbiM protein.
       0.470
ADB47377.1
PFAM: cobalt transport protein; KEGG: hmo:HM1_3001 cobalt abc transporter, permease protein CbiQ.
       0.470
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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