STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADB47394.1Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (317 aa)    
Predicted Functional Partners:
ADB47395.1
PFAM: protein of unknown function DUF322; KEGG: cth:Cthe_2070 hypothetical protein.
       0.773
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
  
0.723
ADB47396.1
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: dae:Dtox_4086 PHP domain protein.
       0.714
mprF
Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.522
ADB47392.1
PFAM: NAD-dependent epimerase/dehydratase; KEGG: csc:Csac_1597 NAD-dependent epimerase/dehydratase.
       0.504
ADB47397.1
Hypothetical protein.
       0.479
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay.
      
 0.458
ADB47391.1
TIGRFAM: TRAP transporter solute receptor, TAXI family; PFAM: NMT1/THI5 like domain protein; KEGG: drm:Dred_3213 TRAP transporter solute receptor TAXI family protein.
       0.450
ADB47398.1
KEGG: dda:Dd703_0812 hypothetical protein.
       0.449
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
   
 0.437
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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