STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADB47489.1PFAM: integrase family protein; Tn916 integrase domain protein DNA binding; KEGG: sss:SSUSC84_0823 integrase; Belongs to the 'phage' integrase family. (430 aa)    
Predicted Functional Partners:
ADB47490.1
PFAM: Excisionase from transposon Tn916; KEGG: cdf:CD0356 excisionase.
 
   
 0.904
ADB47427.1
PFAM: Excisionase from transposon Tn916; KEGG: sss:SSUSC84_0824 excisionase.
 
   
 0.784
ADB47260.1
PFAM: FeoA family protein; KEGG: cpy:Cphy_3525 FeoA family protein.
  
     0.505
ADB47267.1
KEGG: shi:Shel_25490 protein of unknown function (DUF1858).
  
     0.471
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.463
ADB47825.1
KEGG: tgr:Tgr7_0129 competence protein F.
   
    0.424
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
    0.403
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.