Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB47515.1TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: shi:Shel_12070 permease, glycerol uptake facilitator; Belongs to the MIP/aquaporin (TC 1.A.8) family. (219 aa)    
Predicted Functional Partners:
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
    
   0.807
ADB46980.1
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: mmy:MSC_1062 AAA ATPase family protein.
   
   0.802
ADB46602.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.792
ADB46721.1
KEGG: ele:Elen_3041 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
  
 
   0.678
ADB47403.1
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose- specific IIB subunit; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; KEGG: cbt:CLH_2044 heat-responsive suppressor HrsA.
   
  
 0.654
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.649
ADB47429.1
PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: mei:Msip34_0959 heat shock protein DnaJ domain protein.
   
 
 0.649
ADB47424.1
KEGG: cce:Ccel_2968 hypothetical protein.
    
   0.629
ADB46858.1
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bbe:BBR47_00410 PTS system IIA component.
  
  
 0.609
ADB46731.1
KEGG: bay:RBAM_036150 hypothetical protein.
    
   0.590
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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