Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB47561.1PFAM: thiamine monophosphate synthase; KEGG: ere:EUBREC_0222 thiamine-phosphate pyrophosphorylase, putative. (189 aa)    
Predicted Functional Partners:
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
 
 0.939
ADB46865.1
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: esi:Exig_0540 phosphomethylpyrimidine kinase.
 
 
 0.934
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.762
ADB46633.1
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: bvu:BVU_0349 thiamine biosynthesis protein ThiH.
  
  
 0.700
ADB47559.1
deoxyUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
    0.595
ADB47558.1
Hypothetical protein.
       0.592
ADB47560.1
Hypothetical protein.
       0.592
ADB47562.1
PFAM: Desulfoferrodoxin ferrous iron-binding region; KEGG: cpy:Cphy_1924 desulfoferrodoxin ferrous iron- binding region.
       0.459
ADB47697.1
PFAM: PP-loop domain protein; SMART: Rhodanese domain protein; KEGG: ere:EUBREC_1362 putative ATPase of the PP- loop superfamily implicated in cell cycle control; Belongs to the TtcA family.
   
 
 0.440
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.421
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.