Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB47646.1Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: lbu:LBUL_0889 C-di-GMP-specific phosphodiesterase. (558 aa)    
Predicted Functional Partners:
ADB47187.1
Diguanylate cyclase with PAS/PAC sensor; KEGG: pca:Pcar_0936 GGDEF domain-containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein.
 
 0.990
ADB47800.1
Diguanylate cyclase; KEGG: cdf:CD0522 putative signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 0.975
ADB47746.1
Diguanylate cyclase; KEGG: gtn:GTNG_0884 methyl-accepting chemotaxis protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.827
ADB47747.1
KEGG: mpt:Mpe_A0214 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein.
 
 
 0.825
ADB47077.1
KEGG: rca:Rcas_1163 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.679
ADB47055.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: glo:Glov_0565 multi-sensor hybrid histidine kinase.
 
  
 0.657
ADB47817.1
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eat:EAT1b_1042 diguanylate cyclase and metal dependent phosphohydrolase.
 
  
 0.600
ADB47645.1
PFAM: peptidase U32; KEGG: pth:PTH_1944 collagenase and related proteases.
       0.480
ADB47548.1
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: nth:Nther_2317 response regulator receiver protein.
  
    0.436
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.