Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADB47807.1TIGRFAM: pur operon repressor; PFAM: purine repressor; phosphoribosyltransferase; KEGG: hor:Hore_21340 purine operon repressor, PurR. (270 aa)    
Predicted Functional Partners:
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
  
 0.793
ispE
4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
    0.792
ADB47808.1
Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: drm:Dred_0095 GntR family transcriptional regulator.
       0.777
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.709
ADB47291.1
KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
  
  
 0.700
ADB47806.1
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: gka:GK1591 threonine dehydratase.
  
    0.672
ADB47810.1
PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; KEGG: tpd:Teth39_1269 hypothetical protein.
 
    0.509
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
  
 0.490
ADB47314.1
Transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; KEGG: tte:TTE1763 transcriptional regulator.
  
   
 0.476
ADB47756.1
PFAM: regulatory protein DeoR; KEGG: tte:TTE1477 fatty acid biosynthesis transcriptional regulator.
  
    0.469
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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