| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADB46759.1 | ADB47917.1 | Acfer_0353 | Acfer_1559 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.409 |
| ADB46759.1 | guaA | Acfer_0353 | Acfer_0670 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.738 |
| ADB46759.1 | nadD | Acfer_0353 | Acfer_0142 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.591 |
| ADB47092.1 | ADB47917.1 | Acfer_0700 | Acfer_1559 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.534 |
| ADB47092.1 | nadD | Acfer_0700 | Acfer_0142 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.950 |
| ADB47914.1 | ADB47916.1 | Acfer_1556 | Acfer_1558 | Beta-lactamase class A-like protein; KEGG: ddr:Deide_20680 putative beta-lactamase (penicillinase). | PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: afl:Aflv_2310 hemolysin related protein containing CBS domains. | 0.561 |
| ADB47914.1 | ADB47917.1 | Acfer_1556 | Acfer_1559 | Beta-lactamase class A-like protein; KEGG: ddr:Deide_20680 putative beta-lactamase (penicillinase). | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.417 |
| ADB47916.1 | ADB47914.1 | Acfer_1558 | Acfer_1556 | PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: afl:Aflv_2310 hemolysin related protein containing CBS domains. | Beta-lactamase class A-like protein; KEGG: ddr:Deide_20680 putative beta-lactamase (penicillinase). | 0.561 |
| ADB47916.1 | ADB47917.1 | Acfer_1558 | Acfer_1559 | PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: afl:Aflv_2310 hemolysin related protein containing CBS domains. | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.524 |
| ADB47917.1 | ADB46759.1 | Acfer_1559 | Acfer_0353 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.409 |
| ADB47917.1 | ADB47092.1 | Acfer_1559 | Acfer_0700 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.534 |
| ADB47917.1 | ADB47914.1 | Acfer_1559 | Acfer_1556 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | Beta-lactamase class A-like protein; KEGG: ddr:Deide_20680 putative beta-lactamase (penicillinase). | 0.417 |
| ADB47917.1 | ADB47916.1 | Acfer_1559 | Acfer_1558 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; KEGG: afl:Aflv_2310 hemolysin related protein containing CBS domains. | 0.524 |
| ADB47917.1 | gpsA | Acfer_1559 | Acfer_1235 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: stp:Strop_1266 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.546 |
| ADB47917.1 | guaA | Acfer_1559 | Acfer_0670 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.480 |
| ADB47917.1 | nadD | Acfer_1559 | Acfer_0142 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.405 |
| ADB47917.1 | nnrD | Acfer_1559 | Acfer_1628 | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.478 |
| gpsA | ADB47917.1 | Acfer_1235 | Acfer_1559 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: stp:Strop_1266 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.546 |
| guaA | ADB46759.1 | Acfer_0670 | Acfer_0353 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.738 |
| guaA | ADB47917.1 | Acfer_0670 | Acfer_1559 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: isochorismatase hydrolase; KEGG: dhd:Dhaf_2040 isochorismatase hydrolase. | 0.480 |