Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
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gene fusions
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tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (339 aa)    
Predicted Functional Partners:
ADB47938.1
PFAM: protein of unknown function UPF0079; KEGG: cdf:CD0149 putative ATP/GTP hydrolase.
 
 0.994
ADB47937.1
PFAM: peptidase M22 glycoprotease; KEGG: cce:Ccel_0800 peptidase M22 glycoprotease.
 
 
 0.983
ADB47936.1
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
  
  
 0.837
ADB47200.1
Hypothetical protein; KEGG: cco:CCC13826_0299 spore coat polysaccharide biosynthesis protein SpsC-like protein.
  
 0.762
ADB46826.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
 0.648
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
      0.525
mnmA
tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
   
 0.520
ADB47031.1
KEGG: cth:Cthe_2105 DNA polymerase III, delta prime subunit.
 
   
 0.487
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.487
ADB47934.1
PFAM: transposase IS4 family protein; KEGG: dsy:DSY1297 hypothetical protein.
       0.486
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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