Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB47961.1Glycerate kinase; PFAM: MOFRL domain protein; KEGG: cpy:Cphy_2103 hydroxypyruvate reductase. (409 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.915
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate- independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.901
ADB46956.1
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; KEGG: bbe:BBR47_13840 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.852
ADB47407.1
PFAM: Lactate/malate dehydrogenase; KEGG: blt:Balat_0321 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
  
 0.837
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.812
ADB48139.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
  0.810
ADB46988.1
PFAM: phosphoglucose isomerase (PGI); KEGG: hor:Hore_19060 glucose-6-phosphate isomerase.
    
  0.805
ADB46484.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: nth:Nther_1482 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
     
  0.800
ADB46485.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: tte:TTE1341 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
  0.800
ADB46858.1
TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; KEGG: bbe:BBR47_00410 PTS system IIA component.
     
  0.800
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.