Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa)    
Predicted Functional Partners:
ADB48119.1
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: cth:Cthe_2799 cystathionine gamma-synthase.
 
 
 0.967
ADB46473.1
KEGG: cbe:Cbei_0766 O-acetylhomoserine/O- acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein.
 
 
 0.960
ADB47594.1
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; KEGG: hmo:HM1_1936 homoserine dehydrogenase.
  
 
 0.940
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
    
 0.914
ADB48206.1
PFAM: methylenetetrahydrofolate reductase; KEGG: ank:AnaeK_2769 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.828
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.816
ADB47806.1
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: gka:GK1591 threonine dehydratase.
   
 
 0.809
ADB46818.1
KEGG: tde:TDE1506 L-serine dehydratase, iron-sulfur- dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain.
     
 0.803
ADB46819.1
KEGG: tde:TDE1507 L-serine dehydratase, iron-sulfur- dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain.
     
 0.803
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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