| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADB47083.1 | murI | Acfer_0691 | Acfer_0031 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.907 |
| ADB47083.1 | murI-2 | Acfer_0691 | Acfer_1754 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.777 |
| ADB47688.1 | ADB47943.1 | Acfer_1327 | Acfer_1586 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | 0.918 |
| ADB47688.1 | ADB48112.1 | Acfer_1327 | Acfer_1756 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.914 |
| ADB47688.1 | ADB48402.1 | Acfer_1327 | Acfer_2057 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cpy:Cphy_3412 putative oxidoreductase. | 0.912 |
| ADB47688.1 | glsA | Acfer_1327 | Acfer_0049 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | PFAM: Glutaminase, core; KEGG: cpr:CPR_1963 glutaminase; Belongs to the glutaminase family. | 0.905 |
| ADB47688.1 | murI | Acfer_1327 | Acfer_0031 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| ADB47688.1 | murI-2 | Acfer_1327 | Acfer_1754 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| ADB47943.1 | ADB47688.1 | Acfer_1586 | Acfer_1327 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | 0.918 |
| ADB47943.1 | ADB48112.1 | Acfer_1586 | Acfer_1756 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.935 |
| ADB47943.1 | ADB48402.1 | Acfer_1586 | Acfer_2057 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cpy:Cphy_3412 putative oxidoreductase. | 0.918 |
| ADB47943.1 | glsA | Acfer_1586 | Acfer_0049 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | PFAM: Glutaminase, core; KEGG: cpr:CPR_1963 glutaminase; Belongs to the glutaminase family. | 0.918 |
| ADB47943.1 | murI | Acfer_1586 | Acfer_0031 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.828 |
| ADB47943.1 | murI-2 | Acfer_1586 | Acfer_1754 | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.828 |
| ADB48112.1 | ADB47688.1 | Acfer_1756 | Acfer_1327 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_0372 sulfide dehydrogenase (flavoprotein) subunit SudA. | 0.914 |
| ADB48112.1 | ADB47943.1 | Acfer_1756 | Acfer_1586 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: glutamine synthetase catalytic region; KEGG: cpf:CPF_2894 putative glutamine synthetase. | 0.935 |
| ADB48112.1 | ADB48402.1 | Acfer_1756 | Acfer_2057 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cpy:Cphy_3412 putative oxidoreductase. | 0.914 |
| ADB48112.1 | glsA | Acfer_1756 | Acfer_0049 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | PFAM: Glutaminase, core; KEGG: cpr:CPR_1963 glutaminase; Belongs to the glutaminase family. | 0.910 |
| ADB48112.1 | murI | Acfer_1756 | Acfer_0031 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.823 |
| ADB48112.1 | murI-2 | Acfer_1756 | Acfer_1754 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: fno:Fnod_1064 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.823 |