Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADB48161.1Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (177 aa)    
Predicted Functional Partners:
ADB48162.1
KEGG: cpy:Cphy_3050 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; formate C- acetyltransferase glycine radical.
 
 
 0.992
ADB47564.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; glutaredoxin; KEGG: shi:Shel_18290 anaerobic ribonucleoside- triphosphate reductase.
  
 
 0.749
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.586
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
  
  
 0.536
ADB47588.1
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cbi:CLJ_B0869 putative 6-pyruvoyl tetrahydropterin synthase.
  
  
 0.530
ADB47999.1
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: bvu:BVU_2082 6-pyruvoyl-tetrahydropterin synthase.
  
  
 0.530
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.495
ADB48160.1
Amidohydrolase; KEGG: nis:NIS_1768 N-acetyl-L-amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein.
       0.400
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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