STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
gcdACarboxyl transferase; Decarboxylase subunit of the primary sodium pump glutaconyl- CoA decarboxylase (GCD). (587 aa)    
Predicted Functional Partners:
gcdC
Biotin/lipoyl attachment domain-containing protein; Biotin carrier subunit of the primary sodium pump glutaconyl- CoA decarboxylase (GCD).
 
 
 0.948
gcdD
Sodium pump decarboxylase, gamma subunit; Part of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). Possible membrane anchor for the alpha subunit.
    
 0.946
gctB
Coenzyme A transferase; Catalyzes the transfer of the CoA moiety from acetyl-CoA to (R)-2-hydroxyglutarate and related compounds like glutaconate.
 
  
 0.938
gctA
Coenzyme A transferase; Catalyzes the transfer of the CoA moiety from acetyl-CoA to (R)-2-hydroxyglutarate and related compounds like glutaconate.
 
  
 0.938
ADB47836.1
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: chy:CHY_1350 butyryl-CoA dehydrogenase.
 
 
 0.934
gcdB
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD); Belongs to the GcdB/MmdB/OadB family.
 
 
  0.934
ADB46948.1
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: drm:Dred_1781 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.926
ADB47834.1
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: chy:CHY_1601 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.926
ADB47859.1
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
 
 
  0.918
hgdA
2-hydroxyglutaryl-CoA dehydratase D-component; Involved in the fermentation of L-glutamate via the hydroxyglutarate pathway. Catalyzes the reversible syn-elimination of water from (R)-2-hydroxyglutaryl-CoA to yield (E)- glutaconyl-CoA. The dehydration mechanism involves a transient one electron reduction of the thioester from (R)-2-hydroxyglutaryl-CoA, generating a ketyl radical. Prior to (E)-glutaconyl-CoA formation, the ketyl radical is subsequently reoxidized by electron transfer back to the HgdA-HgdB complex (CompD) to avoid change in oxidation state of the substrate. The appropria [...]
 
     0.881
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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