STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADB48210.1PFAM: phosphoribosyltransferase; KEGG: dps:DP1516 adenine phosphoribosyltransferase. (183 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 0.980
ADB46454.1
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; KEGG: bhy:BHWA1_00426 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.937
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.937
ADB47702.1
IMP cyclohydrolase; KEGG: bfr:BF2666 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme formylation region; SMART: AICARFT/IMPCHase bienzyme formylation region.
  
 0.927
ADB47222.1
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: swo:Swol_1594 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterases-like protein; Belongs to the 5'-nucleotidase family.
    
 0.923
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.917
ADB48412.1
PFAM: metallophosphoesterase; KEGG: bcm:Bcenmc03_6434 metallophosphoesterase.
 
 
  0.916
ADB47954.1
KEGG: chy:CHY_1067 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.914
ADB47221.1
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: oan:Oant_2761 inosine/uridine-preferring nucleoside hydrolase.
     
 0.904
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.904
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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