Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (702 aa)    
Predicted Functional Partners:
ADB48213.1
PFAM: Ppx/GppA phosphatase; KEGG: pmo:Pmob_0465 exopolyphosphatase-like protein.
 
  
 0.968
ADB48214.1
PFAM: Ppx/GppA phosphatase; KEGG: drm:Dred_1179 Ppx/GppA phosphatase.
 
 
 0.964
ADB46999.1
Inorganic diphosphatase; PFAM: DHHA2 domain protein; phosphoesterase RecJ domain protein; KEGG: cac:CAC2138 putative manganese-dependent inorganic pyrophosphatase.
     
  0.900
ADB47692.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: esi:Exig_2410 HAD family hydrolase.
   
 
  0.900
ADB47350.1
PFAM: protein of unknown function DUF344; KEGG: cyt:cce_2971 putative polyphosphate kinase 2.
 
   
 0.792
ADB48211.1
Hypothetical protein.
       0.614
ADB46956.1
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; KEGG: bbe:BBR47_13840 pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.489
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.427
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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