Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADB48322.1TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: mta:Moth_1882 aconitate hydratase. (651 aa)    
Predicted Functional Partners:
ADB48319.1
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: efe:EFER_3668 putative isocitrate dehydrogenase.
 
 0.779
ADB48321.1
KEGG: efe:EFER_3663 putative lactonase.
       0.777
ADB48320.1
PFAM: Dicarboxylate carrier MatC domain protein; KEGG: efe:EFER_3664 hypothetical protein; putative membrane protein.
       0.757
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.647
ADB47001.1
KEGG: tte:TTE0387 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.637
ADB46892.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cby:CLM_3126 pyruvate ferredoxin oxidoreductase.
  
  
 0.612
ADB48120.1
KEGG: cce:Ccel_2567 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
 
 0.546
ADB48323.1
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate- binding; KEGG: bbe:BBR47_25340 transcriptional regulator.
       0.516
atpA-2
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.505
ADB47407.1
PFAM: Lactate/malate dehydrogenase; KEGG: blt:Balat_0321 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.482
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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