Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)    
Predicted Functional Partners:
ADB46586.1
PFAM: Aldehyde Dehydrogenase; KEGG: sak:SAK_1211 aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
   
 0.942
ADB46424.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: apv:Apar_1191 malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.938
ADB47085.1
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: chy:CHY_1369 NAD-dependent malic enzyme.
  
 
 0.938
ADB47312.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 
 0.905
ADB47706.1
KEGG: stm:STM3354 L(+)-tartrate dehydratase subunit beta; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
  
 
 0.857
ADB47707.1
KEGG: set:SEN3188 tartrate dehydratase subunit alpha; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
  
 
 0.857
atpA-2
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.826
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pth:PTH_0517 argininosuccinate lyase.
   
 
0.825
ADB46885.1
PFAM: aminotransferase class I and II; KEGG: amt:Amet_2618 aspartate aminotransferase.
   
 0.824
ADB47107.1
PFAM: aminotransferase class I and II; KEGG: cac:CAC2832 aspartate aminotransferase.
   
 0.824
Your Current Organism:
Acidaminococcus fermentans
NCBI taxonomy Id: 591001
Other names: A. fermentans DSM 20731, Acidaminococcus fermentans DSM 20731, Acidaminococcus fermentans str. DSM 20731, Acidaminococcus fermentans strain DSM 20731
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