node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADB47291.1 | ADB48433.1 | Acfer_0906 | Acfer_2089 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | 0.652 |
ADB47291.1 | carA | Acfer_0906 | Acfer_1316 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: amt:Amet_4211 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.945 |
ADB47291.1 | carB | Acfer_0906 | Acfer_1315 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; KEGG: hmo:HM1_2110 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.671 |
ADB47291.1 | pyrB | Acfer_0906 | Acfer_1318 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | KEGG: drm:Dred_1681 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.629 |
ADB47291.1 | pyrC | Acfer_0906 | Acfer_1317 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.543 |
ADB47291.1 | pyrD | Acfer_0906 | Acfer_1313 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.620 |
ADB47291.1 | pyrE | Acfer_0906 | Acfer_1311 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.643 |
ADB47291.1 | pyrF | Acfer_0906 | Acfer_1312 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.604 |
ADB47291.1 | pyrR | Acfer_0906 | Acfer_1507 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.509 |
ADB47291.1 | xpt | Acfer_0906 | Acfer_2090 | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.675 |
ADB48433.1 | ADB47291.1 | Acfer_2089 | Acfer_0906 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | 0.652 |
ADB48433.1 | carA | Acfer_2089 | Acfer_1316 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: amt:Amet_4211 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.618 |
ADB48433.1 | carB | Acfer_2089 | Acfer_1315 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; KEGG: hmo:HM1_2110 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.607 |
ADB48433.1 | pyrB | Acfer_2089 | Acfer_1318 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | KEGG: drm:Dred_1681 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.691 |
ADB48433.1 | pyrC | Acfer_2089 | Acfer_1317 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.666 |
ADB48433.1 | pyrD | Acfer_2089 | Acfer_1313 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.517 |
ADB48433.1 | pyrE | Acfer_2089 | Acfer_1311 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.599 |
ADB48433.1 | pyrF | Acfer_2089 | Acfer_1312 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.632 |
ADB48433.1 | pyrR | Acfer_2089 | Acfer_1507 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.691 |
ADB48433.1 | xpt | Acfer_2089 | Acfer_2090 | TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ele:Elen_2967 xanthine permease. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.990 |