Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (612 aa)    
Predicted Functional Partners:
ADI31766.1
KEGG: reh:H16_B0618 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
 
 
 0.939
ADI32497.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dvm:DvMF_0446 putative glutamate synthase subunit beta.
 
  
 0.931
ADI32028.1
TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; KEGG: ftf:FTF1168c N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase.
    
 0.924
ADI32408.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
  
 
 0.924
ADI32029.1
PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; KEGG: avn:Avin_51890 glucosamine--fructose-6-phosphate aminotransferase, isomerizing; GlmS.
  
  
 
0.912
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.817
ADI31166.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: Hypothetical protein CBG06266.
     
 0.783
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.694
ADI31801.1
KEGG: mlo:mlr1185 succinyl-diaminopimelate desuccinylase; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
   
 
 0.524
ADI32707.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: pnu:Pnuc_1992 UDP-N-acetylglucosamine pyrophosphorylase.
   
 0.523
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (14%) [HD]