Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31195.1alpha-L-glutamate ligase, RimK family; KEGG: aap:NT05HA_1236 ribosomal protein S6 modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201. (312 aa)    
Predicted Functional Partners:
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
    0.867
ADI31193.1
Hypothetical protein.
       0.867
ADI31191.1
PFAM: phosphoribosyltransferase; KEGG: tgr:Tgr7_1686 phosphoribosyltransferase.
       0.834
ADI31194.1
Hypothetical protein.
       0.781
ADI31801.1
KEGG: mlo:mlr1185 succinyl-diaminopimelate desuccinylase; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
  
 0.708
ADI32466.1
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
     0.557
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
    
   0.536
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.501
ADI31538.1
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mmb:Mmol_1342 triphosphoribosyl-dephospho-CoA protein.
 
     0.488
ADI31742.1
KEGG: hypothetical protein; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Protein of unknown function DUF357; cytidylyltransferase.
       0.487
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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