STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31195.1alpha-L-glutamate ligase, RimK family; KEGG: aap:NT05HA_1236 ribosomal protein S6 modification protein; TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: RimK domain protein ATP-grasp; protein of unknown function DUF201. (312 aa)    
Predicted Functional Partners:
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.856
ADI31193.1
Hypothetical protein.
       0.856
ADI31191.1
PFAM: phosphoribosyltransferase; KEGG: tgr:Tgr7_1686 phosphoribosyltransferase.
       0.820
ADI31194.1
Hypothetical protein.
       0.781
ADI32466.1
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
     0.577
ADI31538.1
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mmb:Mmol_1342 triphosphoribosyl-dephospho-CoA protein.
 
     0.492
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.490
ADI31801.1
KEGG: mlo:mlr1185 succinyl-diaminopimelate desuccinylase; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein.
 
  
 0.459
ADI32467.1
Dihydropteroate synthase-related protein; KEGG: mmb:Mmol_0897 dihydropteroate synthase DhpS; TIGRFAM: dihydropteroate synthase-related protein; PFAM: dihydropteroate synthase DHPS.
 
    0.450
ADI31742.1
KEGG: hypothetical protein; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Protein of unknown function DUF357; cytidylyltransferase.
       0.436
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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