Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31214.1PFAM: Methyltransferase type 11; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: gur:Gura_3459 diguanylate cyclase with PAS/PAC sensor. (216 aa)    
Predicted Functional Partners:
ADI31215.1
KEGG: similar to predicted protein; PFAM: Fmu (Sun) domain protein; PUA domain containing protein; SMART: PUA domain containing protein.
  
 
 0.808
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 0.712
ADI31622.1
KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein.
  
 0.653
ADI31288.1
KEGG: geo:Geob_0463 NADH-quinone oxidoreductase, B subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
    
 0.614
ADI31286.1
KEGG: nse:NSE_0566 NADH dehydrogenase subunit D; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; Belongs to the complex I 49 kDa subunit family.
    
 0.590
ADI31213.1
Hypothetical protein.
       0.554
rps9
Ribosomal protein S9P; KEGG: SORBIDRAFT_05g001680; hypothetical protein; TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
  0.527
ADI31942.1
KEGG: conserved hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
   
 
 0.517
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.468
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
   0.463
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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