Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (275 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.935
ADI32061.1
TIGRFAM: cytidyltransferase-related domain protein; KEGG: dac:Daci_5608 cytidyltransferase-like protein; PFAM: cytidylyltransferase.
    
 0.915
ADI32617.1
TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; KEGG: hch:HCH_06993 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; PFAM: cytidylyltransferase.
    
 0.915
ADI31216.1
SMART: Nucleotide binding protein PINc; KEGG: predicted protein; K11883 RNA-binding protein NOB1.
       0.880
ADI31218.1
PFAM: protein of unknown function Met10; KEGG: similar to tRNA-(N1G37) methyltransferase.
       0.740
ADI32464.1
PFAM: protein of unknown function DUF198; KEGG: gbm:Gbem_3692 protein of unknown function DUF198.
 
   
 0.529
ADI31215.1
KEGG: similar to predicted protein; PFAM: Fmu (Sun) domain protein; PUA domain containing protein; SMART: PUA domain containing protein.
  
    0.513
ADI31705.1
KEGG: dihydroorotate dehydrogenase family protein; TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.481
ADI31479.1
PFAM: Quinolinate phosphoribosyl transferase; KEGG: ilo:IL0103 nicotinate phosphoribosyltransferase.
 
  
 0.461
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.436
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.