Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31223.1SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; KEGG: gur:Gura_2842 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein. (738 aa)    
Predicted Functional Partners:
ADI31622.1
KEGG: mxa:MXAN_5045 serine/threonine kinase family protein; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; Pyrrolo-quinoline quinone; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; tyrosine protein kinase; Pyrrolo-quinoline quinone beta-propeller repeat; WD-40 repeat protein.
   
 0.904
ADI32436.1
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; KEGG: rlg:Rleg_7058 AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; AAA ATPase VAT domain protein.
  
  
 
0.902
ADI32371.1
KEGG: maq:Maqu_3834 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily.
   
 0.812
rpl40e
PFAM: Ribosomal protein L40e; KEGG: Ubiquitin/ribosomal protein CEP52; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.754
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 
 0.739
ADI31222.1
Hypothetical protein.
       0.717
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
  0.663
ef1b
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
     
 0.661
ADI31476.1
PFAM: heat shock protein Hsp20; CS; KEGG: gur:Gura_2833 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.657
ADI31942.1
KEGG: conserved hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat.
  
 0.647
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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