STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31227.1PFAM: tRNA pseudouridine synthase D TruD; KEGG: gur:Gura_0971 tRNA pseudouridine synthase D, TruD. (375 aa)    
Predicted Functional Partners:
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
 
     0.896
ADI31161.1
PFAM: GTP-binding protein HSR1-related; KEGG: nucleolar GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
   
   0.762
rpl11
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
   
   0.716
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
   
   0.714
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
   0.712
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.702
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.699
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.690
ADI31299.1
PFAM: RNA polymerase dimerisation; KEGG: similar to DNA-directed RNA polymerase II 13.3 kDa polypeptide (RPB11); K03008 DNA-directed RNA polymerase II subunit J.
 
    0.663
ADI32619.1
KEGG: nucleolar GTP-binding protein 1; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Nucleolar GTP-binding-1 domain protein.
  
  
 0.661
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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