STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nop10RNA-binding protein Nop10p; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (62 aa)    
Predicted Functional Partners:
ADI32304.1
Hypothetical protein.
   
 0.999
rpl7ae
Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.999
eif2a
Translation initiation factor 2, alpha subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
  
  
 0.968
ADI31299.1
PFAM: RNA polymerase dimerisation; KEGG: similar to DNA-directed RNA polymerase II 13.3 kDa polypeptide (RPB11); K03008 DNA-directed RNA polymerase II subunit J.
  
    0.824
ADI31292.1
KEGG: Hypothetical protein CBG09235.
       0.799
ADI32297.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: hypothetical protein.
  
  
 0.654
ADI32450.1
TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; KEGG: similar to RNA-binding protein PNO1; K11884 RNA-binding protein PNO1; SMART: KH domain protein.
   
 
 0.645
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
  
  
 0.642
ADI32123.1
Hypothetical protein.
   
  
 0.595
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.584
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.