STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31306.1PFAM: putative RNA methylase; THUMP domain protein; methyltransferase small; KEGG: similar to THUMP domain containing 3. (348 aa)    
Predicted Functional Partners:
ADI31161.1
PFAM: GTP-binding protein HSR1-related; KEGG: nucleolar GTPase; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
  
 0.598
rpl10e
KEGG: 60S ribosomal protein L10; K02866 large subunit ribosomal protein L10e; TIGRFAM: ribosomal protein L10.e; PFAM: Ribosomal protein L10e/L16; Belongs to the universal ribosomal protein uL16 family.
     
 0.590
uppS
Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
   
    0.577
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.557
ADI31930.1
Arginine--tRNA ligase; KEGG: predicted protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
    0.542
ADI31859.1
PFAM: SMC domain protein; KEGG: viral A-type inclusion protein.
 
    0.524
ADI31304.1
Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
       0.474
tgtA
tRNA-guanine transglycosylase, various specificities; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
  
 0.458
leuS
leucyl-tRNA synthetase; KEGG: similar to CG33123 CG33123-PA; K01869 leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
   0.457
ADI32456.1
TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; KEGG: SORBIDRAFT_06g017040; hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.426
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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