Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADI31315.1PFAM: protein of unknown function DUF126; KEGG: sme:SM_b20269 hypothetical protein. (131 aa)    
Predicted Functional Partners:
ADI31316.1
PFAM: protein of unknown function DUF521; KEGG: bam:Bamb_5490 hypothetical protein.
 
 
 0.999
ADI31317.1
KEGG: bpy:Bphyt_2187 UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein.
 
     0.918
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.901
ADI31318.1
GTPase or GTP-binding protein-like protein; KEGG: AAA family ATPase Grc3 (predicted); K06947.
       0.875
ADI31319.1
Hypothetical protein.
       0.845
tmk
TIGRFAM: thymidylate kinase; KEGG: scl:sce0834 putative thymidylate kinase; PFAM: thymidylate kinase.
       0.757
carS
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.583
ADI31320.1
KEGG: wol:WD0887 DNA repair protein RadA.
       0.567
rnp1
Ribonuclease P, Rpp29; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
  
     0.559
ADI31314.1
KEGG: noc:Noc_2211 transposase IS605; TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB.
       0.545
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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