STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31371.1Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein. (239 aa)    
Predicted Functional Partners:
ADI32215.1
hydroxymethylglutaryl-CoA synthase; KEGG: pfl:PFL_5954 hypothetical protein; TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Belongs to the thiolase-like superfamily. UPF0219 family.
  
    0.763
ADI32214.1
PFAM: protein of unknown function DUF35; KEGG: rme:Rmet_5539 hypothetical protein.
 
    0.642
ADI32129.1
PFAM: Thiolase; KEGG: gur:Gura_4354 thiolase.
  
    0.623
ADI31370.1
Hypothetical protein.
       0.527
ADI32453.1
PFAM: NMD3 family protein.
  
   
 0.496
ADI32454.1
PFAM: Protein of unknown function DUF424.
  
     0.481
ADI31461.1
PFAM: TatD-related deoxyribonuclease.
  
     0.477
ADI32299.1
Transcriptional regulator, XRE family; KEGG: wpi:WPa_0273 putative transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
   
 0.474
carS
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.458
ADI32640.1
PFAM: PUA domain containing protein; SMART: PUA domain containing protein.
  
     0.458
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.