Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31377.1KEGG: sdn:Sden_0583 ParB-like nuclease; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease. (252 aa)    
Predicted Functional Partners:
ADI31380.1
PFAM: aminotransferase class V; aminotransferase class-III; KEGG: gbm:Gbem_0736 aminotransferase class V.
    
 0.938
ADI31581.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cysteine synthase A; K01738 cysteine synthase A.
    
 0.922
ADI31411.1
KEGG: avn:Avin_07410 phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase.
 
  
  0.919
ADI31410.1
KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein.
  
 
 0.831
ADI31379.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: afw:Anae109_2506 D-3-phosphoglycerate dehydrogenase.
     
 0.658
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.599
ADI31831.1
PFAM: extracellular solute-binding protein family 1; KEGG: dze:Dd1591_4126 extracellular solute-binding protein family 1.
  
     0.413
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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