STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI31410.1KEGG: ank:AnaeK_3529 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. (419 aa)    
Predicted Functional Partners:
ADI31764.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pen:PSEEN3862 threonine synthase.
 
 
0.954
ADI32672.1
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: vfi:VF_1458 threonine synthase.
 
 
0.954
ADI31853.1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
0.950
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.937
ADI31411.1
KEGG: avn:Avin_07410 phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase.
    
 0.924
ADI31519.1
Methionine synthase II (cobalamin-independent)-like protein; KEGG: cha:CHAB381_1170 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
 
 0.858
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.850
ADI32107.1
KEGG: sfu:Sfum_2792 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
    
 0.832
ADI32549.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: sfu:Sfum_0543 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
    
 0.832
ADI32104.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0325 thiamine pyrophosphate binding domain-containing protein.
    
 0.831
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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