Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI31442.1PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: hypothetical protein LOC100248560. (242 aa)    
Predicted Functional Partners:
ADI31441.1
PFAM: Polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
    0.653
ADI31198.1
PFAM: Rhomboid family protein; KEGG: mxa:MXAN_0661 S54 family peptidase.
  
  
 0.596
ADI31443.1
PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mfa:Mfla_0250 hexulose-6-phosphate synthase.
       0.548
ADI31440.1
PFAM: protein of unknown function DUF134; KEGG: tau:Tola_0308 protein of unknown function DUF134.
       0.524
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.495
ADI32638.1
Transcriptional regulator, XRE family; KEGG: SORBIDRAFT_10g023010; hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
   
 
 0.485
ADI31439.1
PFAM: Protein of unknown function DUF504.
       0.463
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.425
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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